The Titans host their first divisional game of 2021 on Sept. 26 and could get their first look at veteran quarterback Carson Wentz since he was traded from Philadelphia and reunited with Colts head coach and former Eagles offensive coordinator Frank Reich. The Titans enter 2021 with a three-game winning streak within the AFC South after taking all three road matchups with divisional foes in 2020.

Players and Coaches to Know

Indianapolis Colts

Head Coach: Frank Reich
Quarterback: Carson Wentz
Key Players: WR Michael Pittman Jr., G Quenton Nelson, DE Kwity Paye

Tennessee Titans

Head Coach: Mike Vrabel
Quarterback: Ryan Tannehill
Key Players: RB Derrick Henry, WR A.J. Brown